Journal: Frontiers in Immunology
Article Title: IFN-γ induced the formation of foamy macrophages via CD40 signal to control Mycobacterium abscessus pulmonary infection
doi: 10.3389/fimmu.2025.1697443
Figure Lengend Snippet: The correlation between serum IFN-γ and sCD40 levels in MAB-PD patients. (A) Serum sCD40 levels in healthy donors and in patients with stable or active MAB-PD. (B) Correlation between serum IFN-γ and sCD40 levels (R²=0.4398, p = 0.0003). (C-E) Serum sCD40L, TAG, and T-CHO levels in healthy donors and in patients with stable or active MAB-PD. Data are presented as mean ± SEM, and p- values were determined using an unpaired two-tailed Student’s t-test (A, E) . The Pearson correlation coefficient was used to investigate the relationship between serum IFN-γ and sCD40 levels (B) . Statistical significance was set at * p < 0.05. MAB-PD, M.abscessus pulmonary disease.
Article Snippet: The serum levels of IFN-γ and sCD40L were quantified using an IFN-γ and sCD40L ELISA Assay kits, respectively (Multisciences, Zhejiang, China).
Techniques: Two Tailed Test